PRP

PRP Proves Just as Effective in Early an...
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IntroductionReports have concluded that platelet-rich plasma (PRP) is an effective and safe biological approach to treating knee osteoarthritis (OA). However, the effectiveness of PRP in advanced stages of the disease is not entirely clear. The purpose of this study was to evaluate whether the use of PRP would be as effective in studies with early-moderate knee OA patients compared to studies including patients with end-stage OA, based on the Kellgren–Lawrence classification.Materials and methodsA comprehensive search in MEDLINE, EMBASE, Scopus, and Web of Science databases was conducted to identify randomized controlled trials (RCTs) comparing the effect of PRP injections versus other intra-articular treatments on pain and functionality. A meta-analysis was conducted using a random-effects model and the generic inverse variance method.ResultsWe included 31 clinical trials that reported data from 2705 subjects. Meta-analysis revealed an overall significant improvement of both pain and function, favouring PRP. Subanalysis for pain and functional improvement showed significant pain relief in studies with 1–3 and 1–4 Kellgren–Lawrence OA stages and a significant functional improvement in studies with 1–2, 1–3 and 1–4 knee OA stages, favouring PRP.ConclusionOur results indicate that including patients with advanced knee OA does not seem to affect the outcomes of clinical trials in which the effectiveness of the PRP in knee OA is assessed.Click here to read more. Make an Enquiry
ESSKA Orthobiologic Initiative (ORBIT): ...
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In recent years, there has been a growing interest in biologic approaches for tissue healing in various musculoskeletal (MSK) conditions and pathologies, resulting in the emergence of the field of Orthobiologics. This interest has been reflected in the significant surge in research in the MSK medicine field, with numerous pre-clinical studies demonstrating promising evidence from a considerable number of basic science pre-clinical studies, which also translated to promising results in clinical studies.Orthobiologics offer diverse non-operative solutions and can also be used in conjunction with surgical approaches. Platelet Rich Plasma (PRP) products and cell-based therapies (also known as “stem cell therapy”) have been the primary biologic products that have garnered the most attention.The increasing demand from patients to explore non-surgical options before resorting to invasive treatments, coupled with the industry’s investment in accommodating these needs, has heightened interest in orthobiologics. Orthobiologic products have shown potential in regenerating damaged cells and tissues, as well as regulating degenerative processes, and have been effective in improving function and reducing pain in various musculoskeletal (MSK) conditions. This has led to a surge in the use of orthobiologic treatments worldwide that appears to be continuously growing.However, the clinical use of biologic therapies has exceeded the available evidence and supportive research, leading to a surplus of information and misinformation. Some clinicians lack sufficient education, experience, and training in this field, with much of the available information provided by the industry. That is why here at The Regenerative Clinic, we only work with those consultants responsible for teaching other clinicians around the world. We stick with the bests.The ESSKA Orthobologics Initiative (ORBIT) initiative aims to investigate the detailed mechanisms of action of different orthobiologics in pre-clinical models to determine their potential disease-modifying effects. By conducting systematic reviews on the various available orthobiologic products in OA, the initiative’s first study analysed the disease-modifying effects of PRP for knee OA. This review included 44 studies involving over 1200 animals, which showed that PRP injections had clinical effects in 80% of the studies and disease-modifying effects in 68% of the studies. Here at The Regenerative Clinic, our patient success rate is 86% based on data pulled from over 3,000 patients. Full Article If you or someone you know is experiencing joint pain, we can help!We offer a range of orthobiolocigal treatments that use a person’s own harvested cells.Treatments include:MFAT – Micro-fragmented fat – Adipose Tissue therapy and treatment: a pioneering new treatment for pain and inflammation is a new minimally invasive treatment that harnesses natural repair cells removed from your own body fat to target problems affecting the tendons, ligaments, joints and muscles, including osteoarthritis.BMAC – Bone Marrow Aspirate Concentrate (BMAC) is a non-surgical, minimally invasive, regenerative treatment that harnesses the natural ability to heal the body through the assistance of biological growth factors. BMAC utilises the regenerative mesenchymal stem cells collected from bone marrow to aid in the acceleration of healing moderate to severe osteoarthritis and tendon injuries.PRP – Platelet Rich Plasma (PRP) therapy is also known as Autologous Conditioned Plasma. PRP takes advantage of your blood’s natural healing properties to repair damaged cartilage, tendons, ligaments, muscle and bone. It can reduce pain, improve joint function and help you return quickly to normal activities.nSTRIDE – The treatment is designed to be a single injection therapy in the outpatient clinic setting. Blood is withdrawn like a simple blood test, the clinician processes the patient’s blood to concentrate white blood cells, platelets, and plasma proteins into a small volume of plasma. Make an Enquiry
World’s largest analysis of orthobiolo...
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New research into the largest number of studies on the effects of Orthobiologics shows that on average 70% of people who underwent Orthobiologic treatments had a favourable result. The outcomes overall show significant improvements like less pain and more mobility in over 70% of treated individuals.The analysis was conducted by Professor Mark Slevin, Professor of Cell Pathology at Manchester Metropolitan University. Professor Slevin analysed eighteen separate peer-reviewed and published global studies. Professor Slevin said, “There is a growing body of scientific evidence that is cementing the case of Orthobiologic treatments, especially for osteoarthritis and musculoskeletal (MSK) trauma, injury and degeneration. We are looking at the start of potentially an entirely new pathway of treatment that will enhance natural healing using the body’s own tissue and delay the need for more serious surgical intervention. We stand at the beginning of a huge new movement and for the very first time we now have a body of scientific evidence to prove the potential of these treatments.”Professor Slevin continues, “We note that although overall success globally is 70% the rate of success measured at The Regenerative Clinic, London is 84% successful for all procedures combined.” Read more Orthobiologic treatments use a person’s own cells which are harvested, processed by clinicians, and then using ultrasound-guided injection, inserted into the problem area.Treatments include:MFAT – Micro-fragmented fat – Adipose Tissue therapy and treatment: a pioneering new treatment for pain and inflammation is a new minimally invasive treatment that harnesses natural repair cells removed from your own body fat to target problems affecting the tendons, ligaments, joints and muscles, including osteoarthritis.BMAC – Bone Marrow Aspirate Concentrate (BMAC) is a non-surgical, minimally invasive, regenerative treatment that harnesses the natural ability to heal the body through the assistance of biological growth factors. BMAC utilises the regenerative mesenchymal stem cells collected from bone marrow to aid in the acceleration of healing moderate to severe osteoarthritis and tendon injuries.PRP – Platelet Rich Plasma (PRP) therapy is also known as Autologous Conditioned Plasma. PRP takes advantage of your blood’s natural healing properties to repair damaged cartilage, tendons, ligaments, muscle and bone. It can reduce pain, improve joint function and help you return quickly to normal activities.nSTRIDE – The treatment is designed to be a single injection therapy in the outpatient clinic setting. Blood is withdrawn like a simple blood test, the clinician processes the patient’s blood to concentrate white blood cells, platelets, and plasma proteins into a small volume of plasma. Make an Enquiry
nSTRIDE Autologous Protein Injections
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The nSTRIDE Autologous Protein Injections (nSTRIDE APS) treatment is designed to alleviate pain and bring balance back to your inflamed knee joint by introducing high levels of “good” proteins concentrated in your blood. These good proteins can block the “bad” proteins responsible for the inflammatory condition in your joint. In an osteoarthritic knee, inflammatory cytokines (“bad” proteins) outnumber anti-inflammatory cytokines (“good” proteins) causing an imbalance. This is what causes knee pain and cartilage degeneration.We will take a blood withdrawal like a simple blood test. Your clinician will process your blood to concentrate white blood cells, platelets, and plasma proteins into a small volume of plasma. This will then be administered as a joint injection directly into the knee joint cavity.The treatment is designed to be a single injection therapy in the outpatient clinic setting. This procedure can help with: Anti-inflammatory effectsJoint pain reductionPromotion of cartilage healthImprovement of joint functionThis is a highly successful procedure that significantly reduces pain associated with knee osteoarthritis and significantly improves mobility in the knee joint. It has a proven success rate of 70% improvement in knee pain at 2 years following a single injection.Our Consultant in Regenerative Orthopaedics & Sports Medicine, Dr Ralph Rogers, performs the nSTRIDE APS injection treatment as well as Paul Lee, and Suresh Sudula. Dr Rogers has worked for The Football Association, Chelsea FC, Walsall FC, Warwickshire County Cricket Club and Birmingham Bullets basketball team. Internationally, he is a medical advisor to the National Basketball Association (NBA) and has recently been appointed to serve as an independent non-executive medical doctor for the Kenyan national football team (KPL). Make an Enquiry
Platelet Rich Plasma (PRP) Injections
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Platelet Rich Plasma (PRP) therapy takes advantage of your blood’s natural healing properties to repair damaged cartilage, tendons, ligaments, muscle and bone. The PRP procedure involves taking a blood sample from a vein in your arm and then spinning the blood sample in a centrifuge machine to separate the desired components. Your blood is mostly liquid plasma but also contains solid components, including red cells, white cells and platelets. Platelets are vital in the healing of injuries and are separated in the centrifuge machine. The concentration of platelets is injected into your treatment site.PRP treatment is performed in our outpatient clinic and can take up to an hour to complete. The treatment is generally administered at three weekly intervals and since the treatment is prepared from your own blood, it carries a low risk. The number of injections required depends on the injury but can range from two to six injections.PRP Injections are effective in many areas of the body, limbs and joints such as the shoulder, knee, hip, back and spine, leg, foot, arm, elbow, toes, fingers, hand, thumb and neck.This treatment is widely researched and supported in clinical papers. See our PRP evidence section. Make an Enquiry Conditions and injuries treated with PRPThis simple outpatient treatment may help you recover from a painful sports Injury or chronic pain caused by osteoarthritis and tendinitis. A list of common conditions PRP can help are below: Arthritis (osteoarthritis) Knee Arthritis Hip Arthritis Shoulder Arthritis Ankle Arthritis Tendon/Ligament/Sports Injury Tendinopathy Tennis Elbow/Golfers Elbow Runners Knee/Jumpers Knee Plantar Fasciitis Achilles Tendonitis Shoulder Rotator Cuff Tear Muscle Strain, Contusion and Torn Muscle Fibre Back Pain Neck Pain Lower Back Pain
Are You Suffering With Jaw Pain?
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If you’ve been told your only option for jaw pain is steroid injections or invasive surgery, then minimally invasive regenerative alternatives…

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