Lipogems® is a new and innovative treatment that has helped over 35,000 patients worldwide. It has been extensively researched, please see some of the key clinical papers below for more information.
PRP therapy is an effective and well researched treatment. It has been widely used in sport injuries as well as in aesthetic medicine. To find out more, please see the clinical evidence below.
To see how the treatment could help you make an appointment our multidisciplinary team or call 0330 2233332 for more information.
Dr. Mikel Sánchez explains how his recent study supports the safety and efficacy of PRP for pain relief and improved function in patients with osteoarthritis in the hip.
Dr. Konrad Slynarski speaks to the Regenerative Clinic about his extensive experience using micro-fragmented adipose tissue stem cells in joint preservation and three year clinical studies in the field.
Clinical Papers
Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design
Elevated Monocytes in Patients with Critical Limb Ischemia Diminish after Bypass Surgery
Synovial Tissue Macrophages: Friend or Foe?
Macrophage Cell Lines Produce Osteoinductive Signals That Include Bone Morphogenetic protein-2
Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury
Changes in Macrophage Phenotype and Induction of Epithelial-To-Mesenchymal Transition Genes Following Acute Achilles Tenotomy and Repair
Micro Fragmented Adipose Tissue Promotes the Matrix Synthesis Function of Nucleus Pulposus Cells and Regenerates Degenerated Intervertebral Disc in a Pig Model
Functional Outcomes Following Microfragmented Adipose Tissue Versus Bone Marrow Aspirate Concentrate Injections for Symptomatic Knee Osteoarthritis
MFAT vs. BMAC: Mesenchymal Stem Cell Therapy Showdown for Osteoarthritis Treatment
A 24-Month Follow-Up Study of the Effect of Intra-Articular Injection of Autologous Microfragmented Fat Tissue on Proteoglycan Synthesis in Patients with Knee Osteoarthritis
This paper published in December 2019, reports on patients with advanced knee arthritis treated with Micro-fragmented Fat. The patients were monitored over a 24-month period. Their pain and function were recorded; and all had an MRI scan immediately before the treatment and 24 months after.
17 patients were enrolled and 10 fulfilled the criteria for follow-up. Three had a joint replacement and 4 were lost to follow-up. All of the 10 patients followed-up at 24 months showed a significant reduction in pain and an overall notable increase in the volume of cartilage measured on the contrast-enhanced MRI scan.
This study demonstrates a degree of regeneration of the cartilage which is associated with pain relief in a significant proportion of patients who had a single injection of micro-fragmented fat for knee arthritis.