Cingal® pain relieving injection

Cingal® is a powerful and unique new treatment for osteoarthritis. It is the first pain relieving injection to combine two well-established treatments in a single injection, providing the benefits of both an effective corticosteroid and a high concentration hyaluronic acid. The corticosteroid reduces inflammation in the joint, providing rapid pain relief within days of injection, while the hyaluronic acid component works in parallel to deliver long lasting pain relief proven to last 6 months*.

How it works

Joints affected by osteoarthritis typically have lower concentrations of hyaluronic acid in the synovial fluid, the thick liquid that helps cushion and lubricate the joint. As a result, the synovial fluid in osteoarthritic joints has lower viscosity and elasticity than healthy synovial fluid, decreasing its ability to lubricate the joint and absorb shocks.

Joints that benefit from treatment include:

  • Knees
  • Hips
  • Ankles
  • Spine – neck and lower back
  • Hands – fingers and thumbs
  • Shoulders

When you have osteoarthritis, there may not be enough natural hyaluronan in the joint, and the quality of that hyaluronan may be poorer than normal. Cingal™ is used to supplement (add) hyaluronan to the knee joint. Cingal™ also contains a steroid, triamcinolone hexacetonide, which provides short-term and long-lasting pain relief by reducing inflammation, while the hyaluronan component provides long-lasting pain relief.

“ It is vital to replace some of the lost hyaluronic acid
(HA) in order to help restore healthy joint function. ”

Is it right for me?

Living with osteoarthritis can be painful and debilitating. Osteoarthritis is the most common cause of knee pain. Although there is no cure for the disease, the sooner it has been shown the sooner you start treatment, the more manageable symptoms may become, and the longer they may be able to delay surgery.

The Procedure

Cingal™ is given in a single injection directly into the knee joint providing immediate relief to pain and discomfort. This is done in our out-patient clinic.

Osteoarthritis (OA) is the most common type of arthritis, also known as degenerative joint disease, for which there is no cure. It is a common, chronic, progressive musculoskeletal disorder.

In an osteoarthritic joint, the surface layer of cartilage gradually breaks down and wears away. The bones in the joint that are now exposed rub together, causing pain, swelling, and loss of motion. Over time, the joint may lose its normal shape. In addition, small deposits of bone, called bone spurs, may grow on the edges of the joint. These can break off and float inside the joint space, causing even more pain and damage.

More than 80% of individuals over 50 years old have some radiographic evidence of osteoarthritis. Patients suffering from OA often face chronic pain that worsens over time. Most commonly affecting middle-aged and older people, OA can range from very mild to very severe.

  • Pain
  • Swelling
  • Stiffness
  • Loss of physical function
  • Loss of motion in the joint
  • A crackling sound when moving the joint

1. *Bellamy N, Campbell J, Robinson V, et al. Intraarticular corticosteroid for treatment of osteoarthritis of the knee. Cochrane Database Syst Rev. 2006 Apr 19;(2):CD005328. Review.

2. *Markenson, J., MD. An In-Depth Overview of Osteoarthritis. Hospital for Special Surgery. Web:

3. *Guccione, A.A., et al., The effects of specific medical conditions on the functional limitations of elders in the Framingham Study. American journal of public health, 1994. 84(3): p. 351-8.

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