New study proves that a combination of MFAT and PRP provides effective medium-long-term joint protection for knee osteoarthritis

A new study proves that a combination of MFAT and PRP provides effective medium-long-term joint protection and relief from symptoms in people with knee osteoarthritis.

In this study, the authors prepared micro-fragmented adipose tissue (MFAT) obtained from liposuction and processing using an ACP filter system and combined this with a fully characterized leucocyte-poor platelet-rich plasma (PrP) -produced using the centrifuge.

The conducted clinical trial of 12 individuals with early-moderate knee osteoarthritis, examining 6-month outcomes following ultrasound-guided intraarticular injection of 7mls of the mixture (2ml, MFAT + 5ml PrP).

All patients showed a significant improvement through reduced pain scoring and improvement in function and quality of life- both at rest and during movement or exercise. Contrast-enhanced MRI indicated no further degradation of the joint matrix over the period of the study. Therefore, this combination of MFAT and PrP provides a minimally invasive orthobiological approach for effective medium-long-term joint protection and abrogation of symptoms in people with knee osteoarthritis.

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