Hand & Wrist Stem Cell and PRP Treatment and Therapy

Have you been told your only option for wrist, hand or finger pain is steroid injections or joint fusion surgery?
Minimally invasive regenerative alternatives offer pain relief and can help you get your lifestyle back on track

Stem cell therapy, AMPP® Activated Mesenchymal Pericyte Plasma (using Lipogems® technology) and Platelet Rich Plasma (PRP) treatment can provide relief from pain or a reduced range of motion for people suffering from hand, finger, thumb or wrist arthritis or other conditions of the hand.

Arthritis is the inflammation of one or more of your joints and the most common types are osteoarthritis and rheumatoid arthritis. Osteoarthritis is more common and is caused by the cartilage wearing away. Common symptoms are swelling, stiffness and decreased range of movement. Rheumatoid arthritis is a chronic disease which causes the joint lining to swell and leads to pain and stiffness in the joint. Rheumatoid arthritis often starts in the small joints of the hands and feet.

The hand and wrist have multiple small joints and therefore arthritis can occur in many areas. Thumb arthritis is very common and is wear of the cartilage at the base of the thumb joint, also known as the carpometacarpal joint.

Treatment initially involves anti-inflammatory medicines, splinting and corticosteroid injections.  If these options don’t work, joint fusions (which relieve pain but stop joint motion) or joint replacements can be performed.

Carpal tunnel syndrome causes pain, numbness, and tingling in the hand and arm. It occurs when one of the main nerves to the hand – the median nerve – is squeezed or compressed as it travels through the wrist. 

Initially symptoms can be relieved through wearing a wrist splint or avoiding certain activities.

But if the pressure on the median nerve continues, it can lead to nerve damage and worsening symptoms. To prevent permanent damage, patients may be recommended surgery to take the pressure off the median nerve.

These conditions and other injuries to the wrist, hand and thumb can be treated with stem cell therapy, AMPP® Activated Mesenchymal Pericyte Plasma (using Lipogems® technology) and Platelet Rich Plasma (PRP) treatment which avoids the need for surgery and enables people to return to normal activities sooner.

Hand and wrist conditions which can be treated with AMPP® and PRP therapy include:

  • Hand arthritis
  • Thumb arthritis (basal joint arthritis/carpometacarpal arthritis)
  • Instability
  • Carpal tunnel syndrome
  • Trigger finger
  • TFCC tear

Our hand and wrist specialists: 

London – Mr Ali Noorani

North West – Mr Matthew Smith

South West – Mr Oliver Donaldson

The treatment

AMPP® Activated Mesenchymal Pericyte Plasma (using Lipogems® technology)

At The Regenerative Clinic we exclusively offer our patients AMPP® injections. A pioneering new treatment using your body’s own stem cells from a combination of Lipogems® and Platelet Rich Plasma (PRP) Therapy to treat pain and inflammation. The minimally invasive procedure is a possible alternative to having an operation or can be used after surgery to help healing. It harnesses natural repair cells removed from your body fat to target problems affecting joints, tendons, ligaments and muscles. The procedure takes around an hour and early results suggest an improvement for 75 per cent of suitable patients.

This treatment contains concentrated blood plasma PRP/PRGF, as well as adipose-based pericytes harvested with Lipogems®. Theoretically AMPP® is superior in regeneration and healing. You may have AMPP® in conjunction with the treatment of other joints, the results of which have been very positive.

Read Francine’s story who had Lipogems® treatment in multiple joints including her fingers. Her joints are now perfectly strong and her life has changed completely.

Blood Platelet treatments (PRP)

Platelet Rich Plasma (PRP) supports your body’s self-healing processes by using your own cells. Blood is mostly liquid (called plasma) but also contains solid component including red cells, white cells and platelets. The platelets are important for clotting blood but they also contain proteins called growth factors which are important in the healing of injuries.

With a higher concentration of growth factors than typically found in blood, PRP injections support the restoration of injured tissue and inhibit painful inflammatory processes.

This treatment is widely researched and supported in clinical papers. See our PRP evidence section.

Click to find out more about AMPP® or PRP treatments or make an appointment with one of our specialist orthopaedic consultants.

Our expert team works as part of a collaborative partnership of Surgeons, Sports Medicine doctors and Physiotherapists to provide the perfect patient pathway to get you quickly on the road to recovery. Whether you require conventional treatment or if you are a candidate for these new regenerative treatments, you can be sure that will get the best advice from teaching hospital specialists.

Clinical evidence

Autologous Fat Transfer for Thumb Carpometacarpal Joint Osteoarthritis: A Prospective Study

Background: Most operations for carpometacarpal joint osteoarthritis of the thumb irreversibly alter or destroy the anatomy. There is a high demand for minimally invasive alternatives. The authors report the results of autologous fat transfer for treatment of thumb carpometacarpal joint osteoarthritis. 

Methods: In a prospective study, 50 patients with thumb carpometacarpal joint osteoarthritis were observed for 1 year after autologous fat transfer. Manual liposuction and centrifugation were performed. Pain rating according to visual analogue pain scale; objective force of pinch grip and fist closure; and Disabilities of the Arm, Shoulder, and Hand questionnaire scores before and after treatment were analyzed. 

Results: The average pain in stage 2 patients pre-operatively was 7.7 ± 1.3; it was 1.8 ± 1.9 after 6 months and 2.4 ± 3.1 after 12 months. Patients with stage 2 osteoarthritis demonstrated a superior benefit from this treatment compared with patients with either stage 3 or stage 4 thumb carpo-metacarpal joint osteoarthritis. There were similar improvements for the parameters strength and Disabilities of the Arm, Shoulder, and Hand questionnaire score. No serious adverse events were observed. 

Conclusions: Autologous fat transplantation is an appealing alternative, especially in early-stage basal joint osteoarthritis of the thumb. The low invasiveness of the procedure and early recovery of patients compared with classical procedures such as trapeziectomy, and the superior long-term results compared with classical injection therapy, make this approach feasible as a first-line therapy in early-stage basal joint osteoarthritis of the thumb. (Plast. Reconstr. Surg. 140: 327, 2017.)

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