Differences in exosome content of human adipose tissue processed by non-enzymatic and enzymatic methods

Author: GARCÍA-CONTRERAS, M., et al
Year: 2015


Exosomes (EXOs) are membrane vesicles released by most of cell types. EXOs contain lipids, proteins, and RNA (mRNAs, micro-RNAs, non-coding RNAs). EXOs have been shown to have diagnostic and therapeutic potential. Secreted EXOs transport to other cells and deliver their contents into recipient cells playing a role in cell-to-cell communication. Adipose tissue and adipose-derived stromal cells (ADSCs) represent a promising therapeutic option in regenerative medicine and tissue engineering applications. ADSCs effects on immunomodulation and tissue repair may be attributed to paracrine secreted factors, including EXOs. Here we examine whether human adipose tissue processing methods could affect the EXOs content of the final cell/tissue, comparing non-enzymatic and enzymatic methods.

Get in touch

Find your clinic

We offer appointments nationwide and now working with partners abroad providing cutting edge Regenerative Medicine to patients in Dubai, Australia, Spain and Pakistan.

Sign-up to receive our recent news and the latest developments in regenerative medicine.

You can change your mind at any time by clicking the unsubscribe link in the footer of any email you receive from us, or by contacting us at info@theregenerativeclinic.co.uk. We will treat your information with respect. For more information about our privacy practices please visit our website. By clicking below, you agree that we may process your information in accordance with these terms.

We use Mailchimp as our marketing platform. By clicking below to subscribe, you acknowledge that your information will be transferred to Mailchimp for processing. Learn more about Mailchimp's privacy practices here.